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Imruza 50mg Tablet 10pcs
Azathioprine belongs to the class of cytotoxic immunosuppressants and acts as an immunosuppressive antimetabolite by antagonizing purine metabolism.
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Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
- ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Imruza 50mg Tablet is utilized as an immunosuppressant antimetabolite, either alone or in combination with other agents such as corticosteroids, and procedures that affect the immune response. Its therapeutic effects may take weeks or months to become evident and can include a steroid-sparing effect, thereby reducing the toxicity associated with high doses and prolonged usage of corticosteroids.
It is indicated for:
- Enhancing the survival of organ transplants, including renal, cardiac, and hepatic transplants, and reducing the corticosteroid requirements of renal transplant recipients.
- Treating moderate to severe inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis, in patients requiring corticosteroid therapy, those unable to tolerate corticosteroid therapy, or those with refractory disease to standard first-line therapy.
- Managing various autoimmune diseases, including severe active rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis and polymyositis, autoimmune chronic active hepatitis, pemphigus vulgaris, polyarteritis nodosa, autoimmune hemolytic anemia, and chronic refractory idiopathic thrombocytopenic purpura.
Safety Advices
Alcohol
UNSAFE
It is not known whether it is safe to consume alcohol with Imruza 50. Consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Imruza 50 is unsafe to use during pregnancy due to the risk of harm to the developing baby. However, in life-threatening situations, a doctor may prescribe it if the benefits outweigh the risks. Consult your doctor if you are pregnant or planning pregnancy.
Breastfeeding
CONSULT YOUR DOCTOR
Imruza 50 may pass into breast milk and harm the baby. It is probably unsafe to use during breastfeeding. Consult your doctor.
Driving
CAUTION
It is not known whether Imruza 50 affects driving ability. Avoid driving if you experience symptoms that affect concentration and reaction.
Kidney
CAUTION
Use Imruza 50 with caution in patients with kidney disease. Dose adjustment may be necessary. Consult your doctor.
Liver
CAUTION
Use Imruza 50 with caution in patients with liver disease. Dose adjustment may be needed. Regular monitoring of liver function tests is advisable. Avoid Imruza 50 in severe liver disease.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Composition of Imruza 50mg Tablet
Azathioprine
✔️ Uses of Imruza 50mg Tablet
- Kidney Transplantation
- Rheumatoid Arthritis
✔️ Side Effects of Imruza 50mg Tablet
Common side effects of Imruza 50mg Tablet include infections, depression of bone marrow function, leucopenia, thrombocytopenia, nausea, and hypersensitivity reactions. Rare side effects include neoplasms, hepatotoxicity, and immune system disorders.
✔️ Quick Suggestions:
- Imruza 50mg Tablet should be taken orally at least 1 hour before or 2 hours after consuming milk or dairy products.
- Close monitoring of blood counts is necessary, especially in patients with an inherited deficiency of thiopurine methyltransferase (TPMT).
- Caution is advised in patients with renal and/or hepatic impairment, as well as in patients with Lesch-Nyhan syndrome.
- Special caution is advised in patients with renal dysfunction, and procedures for proper handling and disposal of the drug should be considered.
- Symptoms of overdose may include unexplained infections, ulceration of the throat, bruising, and bleeding, resulting from bone marrow depression. Treatment is supportive, with close monitoring of blood counts.
✔️ Indications of Imruza 50mg Tablet
Imruza 50mg Tablet is used in the management of organ transplantation. It helps the body to accept a transplanted organ like a kidney, liver, heart, lung, or pancreas. It is also useful in some autoimmune diseases including severe inflammatory diseases of the skin, liver, arteries, and blood disorders.
✔️ Pharmacology
Imruza 50mg Tablet antagonizes purine metabolism, potentially inhibiting the synthesis of DNA, RNA, and proteins. It may also interfere with cellular metabolism and inhibit mitosis. Its mechanism of action is likely due to the incorporation of thiopurine analogs into the DNA structure, causing chain termination and cytotoxicity.
✔️ Dosage & Administration of Imruza 50mg Tablet
The dosage of Imruza 50mg Tablet varies depending on the condition being treated. For renal homotransplantation, the initial dose is usually 3 to 5 mg/kg daily, adjusted based on individual patient response. For rheumatoid arthritis, the initial dose is approximately 1.0 mg/kg, with adjustments made based on response and tolerance. Maintenance therapy should be at the lowest effective dose.
✔️ Interaction
Imruza 50mg Tablet may interact with various drugs, including allopurinol, neuromuscular blocking agents, anticoagulants, cytostatic/myelosuppressive agents, methotrexate, vaccines, ribavirin, and aminosalicylate derivatives.
✔️ Contraindications
- If you are allergic to azathioprine or any other ingredients of Imruza 50mg Tablet.
- If you have a severe infection.
- If you have severe liver disease or severe bone marrow disease.
- If you have inflammation of the pancreas.
- If you need or are going to have a vaccination containing a living virus or bacteria, such as BCG, smallpox, or yellow fever vaccine.
- If you are pregnant or are breastfeeding.
✔️ Pregnancy, Fertility & Lactation
Pregnancy:
- Imruza 50mg Tablet is teratogenic, and caution is advised in pregnant women or those likely to become pregnant. Contraceptive precautions should be taken during treatment.
Mutagenicity & Fertility:
- Imruza 50mg Tablet has shown mutagenic effects, and its specific effect on human fertility is unknown.
Lactation:
- Mothers receiving Imruza 50mg Tablet should not breastfeed due to the risk of transmission of the drug and its metabolites to the infant.
✔️ Precautions & Warnings
Monitoring for toxic effects is essential throughout the therapy, especially in patients with renal and/or hepatic impairment. Close monitoring of blood counts is necessary, particularly in individuals with a deficiency of thiopurine methyltransferase (TPMT). Caution is advised in patients with Lesch-Nyhan syndrome.
✔️ Storage Conditions
- Keep the Imruza 50mg Tablet out of the sight and reach of children and pets.
- Store below 30°C in the original package.
- Discard off the expired and unused medicine appropriately.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
